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Adrenaplex™

The adrenal gland requires intake of specific nutrients in order to maintain healthy secretion of key hormones involved with the body’s stress response, including adrenaline and cortisone. Additional supportive nutrients for energy and stress resistance make Adrenaplex an excellent daily supplement to revitalize the adrenal gland and improve the body’s response to stress.* 

Vitamin C

Adrenal glands are rich in vitamin C. During stressful events, they secrete this antioxidant vitamin which may act as protection against oxidative stress.*1 

DHEA

DHEA is a hormone synthesized in the adrenal glands. Supplementation with DHEA has been shown to improve energy and vitality, especially in women who need extra adrenal support. *2-4  

L-tyrosine

The amino acid L-tyrosine helps the body resist the negative effects of stress. *5

Licorice

Licorice prevents the breakdown of adrenal hormones, making them more available to the body. *6 

Pregnenolone

Pregnenolone is a natural hormone produced by the adrenal glands. It is a precursor (building block) for other hormones such as DHEA.*7 

Vitamin B6 (Pyridoxal-5-phosphate)

Pyridoxal-5-phosphate plays a role in the formation of neurotransmitters, including serotonin and dopamine, which play a role in mood and emotion. *9 

Adrenal Extract

Glandular ingredients from animal sources, such as adrenal extract, contain naturally occurring hormones and nutrients which can support human glandular function. *8 

Pantothenic acid

Pantothenic acid Pantothenic acid plays an important role in cellular energy production and in the metabolism of energy from fats. *10 

Rehmannia root

Rehmannia root extract was used in Traditional Chinese Medicine as a tonic, and to increase energy. This herb contains a compound called catalpol which helps stimulate production of adrenal hormones. It has been noted to aid in regulating the activity of the adrenal cortex by promoting the function of the hypothalamus-pituitary-adrenal axis and the release of steroid hormones.*11,12 

References

1. Padayatty SJ, Doppman JL, Chang R, Human adrenal glands secrete vitamin C in response to adrenocorticotrophic hormone. Am J Clin Nutr. 2007;86(1):145-9.

2. Allolio B, Arlt W, Hahner S. DHEA: why, when, and how much--DHEA replacement in adrenal insufficiency. Ann Endocrinol (Paris). 2007;68(4):268-73.

3. Johannsson G, Burman P, Wirén L, et al. Low dose dehydroepiandrosterone affects behavior in hypopituitary androgen-deficient women: a placebo-controlled trial. J Clin Endocrinol Metab. 2002;87(5):2046-52.

4. Binder G, Weber S, Ehrismann M, et al. Effects of dehydroepiandrosterone therapy on pubic hair growth and psychological well-being in adolescent girls and young women with central adrenal insufficiency: a double-blind, randomized, placebo-controlled phase III trial. J Clin Endocrinol Metab. 2009;94(4):1182-90.

5. Deijen JB, Orlebeke JF. Effect of tyrosine on cognitive function and blood pressure under stress. Brain Res Bull. 1994;33(3):319-23

6. Isbrucker RA, Burdock GA. Risk and safety assessment on the consumption of Licorice root (Glycyrrhiza sp.), its extract and powder as a food ingredient, with emphasis on the pharmacology and toxicology of glycyrrhizin. Regul Toxicol Pharmacol. 2006c;46(3):167-92.

7. Soucy P, Luu-The V. Conversion of pregnenolone to DHEA by human 17alpha-hydroxylase/17, 20-lyase (P450c17). Evidence that DHEA is produced from the released intermediate, 17alpha-hydroxypregnenolone. Eur J Biochem. 2000;267(11):3243-7

8. Glandulars. In: Hendler SS, ed. PDR for Nutritional Supplements. 2nd ed. Montvale, NJ: Physician’s Desk Reference; 2008:264.

9. Vitamin B6. In: In: Hendler SS, ed. PDR for Nutritional Supplements. 2nd ed. Montvale, NJ: Physician’s Desk Reference; 2008:634-644

10. Coombs G. Pantothenic Acid. In: The Vitamins: Fundamental Aspects in Nutrition and Health. San Diego, California: Academic Press, Inc; 1992:345-356.

11. Dharmananda S. Rehmannia. Available at: http://www.itmonline.org/arts/rehmann.htm. Accessed on December 3, 2009.

12. Blood tonics. In: Reid DP. Chinese Herbal Medicine. Boston, Mass: Shambala Publications; 1992:150.

FAQ's

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Adrenaplex™

Q: Where do you get your adrenal extracts from?

The adrenal extract is from a bovine source. The cattle are raised in Argentina.

Q: Is the adrenal extract derived just the adrenal gland or is it derived from multi-glandular sources (heart, liver, kidneys, spleen, etc)?

This is a pure adrenal extract. There are no other glandular ingredients added to it.

Q: Can you please provide more details on the purity and testing of the adrenal extract?

The animals used to provide the raw materials are examined before slaughter to ensure they are healthy and suitable for use in a food product. The adrenal glands are dried and the powder is both chemically and microbiologically tested. The supplier provides us with documentation assuring the raw material meets specifications. We also do additional, third party testing on finished products to confirm the information provided by the vendor. Our manufacturing facility is registered with both the United States Department of Agriculture (USDA) and the Food and Drug Administration (FDA).

Q: What is rehmannia?

Rehmannia (Rehmannia glutinosa) or Di Huang is an herb native to northern China. The roots are the beneficial parts of the plant. It is considered a warming herb and a tonic (intended to restore or invigorate) and is used in Traditional Chinese Medicine to tone the blood and restore energy. * 

Q: Should Adrenaplex be taken with meals or on an empty stomach?

Whether to take Adrenaplex with meals or on an empty stomach is a matter of individual preference. Occasionally, some mild stomach upset or nausea may be experienced, in which case we suggest taking this product with food. 

Additional Health Information

Adrenaplex™

Supports Healthy Adrenal Gland Function and Manages Fatigue*

Product Number: 37006 - 60 Capsules

Dietary Supplement

1 to 2 capsules daily or as desired.

The adrenal glands help the body fight against stress and fatigue, and are responsible for controlling stress hormones like cortisol and adrenaline. Adrenaplex™ contains key nutrients essential for healthy adrenal gland function, including highly absorbable freeze-dried adrenal extract, L-Tyrosine, Licorice Extract, Vitamin C, and many other important nutrients that help revitalize the adrenal gland.*

SUPPLEMENT FACTS

Serving Size: 2 Capsules

Servings Per Container: 30 Amount/Serving Daily Value
Vitamin C 200 mg 333%
Pregnenolone 15 mg **
DHEA 10 mg **
Adrenal Extract 450 mg **

(Freeze dried adrenal powder)
L-Tyrosine 450mg **

Licorice (Glycyrrhiza glabra) Root (5:1) Extract

 125 mg **
P5P (Pyridoxal-5-phosphate) 10 mg **
Pantothenic Acid (Calcium Pantothenate) 100 mg 1000%
Rehmannia (Rehmannia glutinosa) Root (5:1) Extract 75 mg **

**Daily Value Not Established.

Other Ingredients: gelatin, cellulose, vegetable source magnesium stearate, silicon dioxide

Contains no: sugar, salt, soy, yeast, wheat, gluten, corn, dairy products, artificial coloring, artificial flavoring or preservatives.

If pregnant or nursing, consult a health care practitioner before using.

Made in the USA

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Did You Know?

The adrenal glands are actually two glands in one. Sitting on top of each kidney, the inner gland is known as the adrenal medulla, while the outer gland is the adrenal cortex. The medulla produces adrenalin. The cortex produces cortisone. The function of the adrenal gland is crucial to how our bodies respond to stress, as the hormones it secretes are what cause the physical changes needed to respond to emergency situations. However, a high-stress life can leave the adrenal glands in need of extra support and nutrition.*

*THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION.
THESE PRODUCTS ARE NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT DISEASE.

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