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Evidence
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Arthocin™

Acetyl-11-Keto-beta-Boswellic Acid, or AKBA, is one of the most potent compounds in boswellia. However, its beneficial support for the body’s natural anti-flammatory response can be partially blocked by another compound found in boswellia – beta boswellic acid. Researchers have found that by removing beta boswellic acid, the effectiveness of the boswellic extract is greatly increased. Arthocin combines this unique extract with curcumin, devil’s claw, and gooseberry, three additional ingredients which help block the activity of inflammatory compounds. *

Boswellia (BosPure)
A unique extract, clinically tested BosPure helps reduce the activity of the inflammatory enzyme, 5-LOX (lipoxygenase). A compound (beta boswellic acid) found in boswellia which interferes with its beneficial activity has been removed, greatly increasing the effectiveness of this extract.*1,2

Curcumin (BCM-95)
Curcumin, a compound found in the spice turmeric, inhibits multiple inflammation pathways in the body. It is also a potent antioxidant. However, curcumin is not well absorbed. The specialized extract in this formula has the highest absorption of any curcumin extract available for maximum health benefits.*3-6

Devil’s claw
The devil’s claw is native to southern Africa. The long, barbed spines on the fruit of this plant are responsible for its descriptive name. Research has found that its beneficial effects are due to its ability to reduce the activation of the inflammatory compound NF-kappaB , as well as inhibit the expression of COX-2.*7-9

Indian gooseberry
Also known as amla, Indian Gooseberry has a long history of use in Ayurvedic medicine. It is a potent antioxidant, and has been shown to support healthy collagen and cartilage formation.*10,11

References

1. Ammon HP. Boswellic acids in chronic inflammatory diseases. Planta Med. 2006;72(12):1100-16.

2. Poeckel D, Tausch L, Altmann A, Induction of central signalling pathways and select functional effects in human platelets by beta-boswellic acid. Br J Pharmacol. 2005;146(4):514-24

3. Jurenka JS. Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research. Altern Med Rev. 2009;14(2):141-53.

4. Jacob A, Wu R, Zhou M, Wang P. Mechanism of the anti-inflammatory effect of curcumin: PPAR-gamma activation. PPAR Res. 2007;89369.

5. Benny B, Antony B. Bioavailability of Biocurcumax (BCM-95). Spice India. September, 2006:11-15.

6. Antony B, Merina B, Iyer VS, Judy N, Lennertz K, Joyal S. A pilot cross-over study to evaluate human oral bioavailability of BCM-95 CG (Biocurcumax™) a novel bioenhanced preparation of curcumin. Ind J Pharm Sci. 2008:445-449.

7. Harpagophytum procumbens (devil's claw). Monograph. Altern Med Rev. 2008;13(3):248-52.

8. Huang TH, Tran VH, Duke RK, et al. Harpagoside suppresses lipopolysaccharide-induced iNOS and COX-2 expression through inhibition of NF-kappa B activation. J Ethnopharmacol. 2006;104(1-2):149-55.

9. Wegener T. Therapy of degenerative diseases of the musculoskeletal system with South African devil's claw (Harpagophytum procumbens DC). Wien Med Wochenschr. 1999;149(8-10):254-7

10. Asmawi MZ, Kankaanranta H, Moilanen E, Vapaatalo H. Anti-inflammatory activities of Emblica officinalis Gaertn leaf extracts. J Pharm Pharmacol. 1993;45(6):581-4.

11. Sumantran VN, Kulkarni A, Chandwaskar R, et al. Chondroprotective potential of fruit extracts of Phyllanthus emblica in osteoarthritis. Evid Based Complement Alternat Med. 2008;5(3):329-335.

FAQ's

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Arthocin™

Q: Q. Can Arthocin be taken with Curamin?

A. Yes, both Arthocin and Curamin can be used together. Curamin is an excellent formula for providing immediate benefits, and Arthocin can be used long-term for daily maintenance.

Additional Health Information

Arthocin™

Clinically Proven Ingredients for Joint and Back Health, Flexibility and Comfort*

Product Number: 20196 - 60 Capsules

Dietary Supplement

1 to 2 capsules daily.

Arthocin™ is a proprietary formula that effectively promotes joint health and regeneration of cartilage by safely inhibiting the COX-2 and 5-LOX enzymes and major signaling and biological pathways of the body.

Combine Arthocin™ with Curamin® for an excellent combination and results.

SUPPLEMENT FACTS

Serving Size: 2 Capsules

Servings Per Container: 30 Amount/Serving Daily Value

Proprietary Joint and Flexibility Formula

1050 mg **

Containing Boswellia BosPure® (Boswellia serrata) Extract standardized to contain >70% boswellic acids with 10-15% AKBA, Curcumin (Curcuma longa) CRX 791 (BCM-95®) Rhizome Extract with curcuminoid complex (curcumin, demethoxycurcumin and bisdemethoxycurcumin), Devils Claw (Harpagophytum procumbens) Extract standardized to contain >20% harpagosides (by HPLC), Indian Gooseberry (Emblica officinalis) Extract standardized to contain >30% total polyphenol content with embilicanins >20%
**Daily Value Not Established.

 

All ingredients established in human studies for safety and effectiveness. Does not interfere with stomach, liver or kidney function.

 

Other Ingredients: cellulose powder, silicon dioxide, vegetable magnesium stearate, vegetable cellulose capsule

Contains no: sugar, salt, yeast, wheat, gluten, corn, soy, artificial coloring, artificial flavoring or preservatives.

BosPure® and BCM-95® are registered trademarks of Dolcas-Biotech.

If pregnant or nursing, consult a health care practitioner before using.

Made in the USA

Europharma
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Did You Know?

The boswellia tree is native to India. It grows in very harsh, dry environments. When the bark of the tree is scraped, it secretes a resin called “tears.” These tears are better known as frankincense. Boswellic acid extracted from the tears of the boswellia tree has been used in Ayurvedic medicine for hundreds of years.

EUROPHARMA USA LIBRARY DISCLAIMER

The research articles and study abstracts that you are about to view in the EuroPharma USA Library were prepared by independent authors and researchers. They are being reproduced on this site in their entirety. No such article or study abstract is intended to promote a particular manufacturer or brand of dietary supplement. This information is not intended to replace the advice of your health care practitioner. If you have any medical conditions, or are taking any prescription or nonprescription medications, see your physician and discuss all aspects of your treatment before altering or discontinuing any course of therapy. Accordingly, individuals must necessarily assume responsibility for their own actions, safety, and health, and the company is not liable or responsible for any loss, injury, or damage allegedly arising from any information posted on this cite.

THIS INFORMATION IS BEING PRESENTED PURSUANT TO SECTION 5 OF THE DIETARY SUPPLEMENT HEALTH AND EDUCATION ACT OF 1994-------THE “E” IN DSHEA—BROUGHT TO YOU AS A PUBLIC SERVICE BY EUROPHARMA USA.