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CardioCare™

The cardiovascular system includes the heart and the blood vessels. The heart contracts (squeezes) which forces blood through the arteries and veins, carrying oxygen to the cells and taking waste material away to be filtered out in the liver and kidneys. A healthy cardiovascular system is one with a strong heart that beats with enough force to push the blood, and flexible, elastic veins and arteries to carry the blood to every cell in the body. The vitamins, minerals and nutrients in CardioCare were carefully selected to promote a strong heart, healthy blood and cholesterol levels already within the normal range, and healthy veins and arteries.*

Vitamin C
Increased intake of vitamin C is associated with beneficial effects for the heart. Preventing oxidative stress from free radical activity with antioxidants such as vitamin C is very important in maintaining cardiovascular health.*1,2

Vitamin E (mixed tocopherols)
Vitamin E promotes heart health through its ability to help prevent the oxidation of LDL cholesterol. This inhibition is greater for mixed tocopherols than for isolated alpha-tocopherol.*3,4

B vitamins: Niacin, Vitamin B6, Vitamin B12, Folic acid
The B vitamins aid in heart health by reducing homocysteine levels. High plasma levels of B vitamins are associated with benefits for cardiovascular health.*5-7

Calcium, magnesium, and potassium
Intake of these minerals is significantly associated with heart health. All play a role in supporting healthy blood pressure levels already within normal limits.*8,9

L-cysteine
Increases cellular energy production in heart cells. L-cysteine improves antioxidant activity by helping protect glutathione (an important antioxidant).*10

CoQ10
Essential for cellular energy production, CoQ10 is especially important for metabolically active cells such as heart cells.*11,12

L-Carnitine HCL
Carnitine is essential for the transport of long-chain fatty acids across the outer- and inner-mitochondrial membranes; the cells of the heart are dependent on a supply of fatty acids for energy production.*13,14

Ginkgo biloba
Ginkgo supports circulation and blood flow*15-17

Nattokinase
Through its effects on fibrinogen levels, nattokinase supports healthy circulation*18,19

EDTA (disodium)
EDTA (ethylenediaminetetraacetic acid ) is a chelating agent. It can bind to heavy metals, such as lead, making them soluble and more readily excreted by the body.*20,21

References

1. Ye Z, Song H. Antioxidant vitamins intake and the risk of coronary heart disease: meta-analysis of cohort studies. Eur J Cardiovasc Prev Rehabil. 2008;15(1):26-34.

2. Block G, Jensen CD, Norkus EP, Hudes M, Crawford PB. Vitamin C in plasma is inversely related to blood pressure and change in blood pressure during the previous year in young Black and White women. Nutr J. 2008;7:35.

3. Pruthi S, Allison TG, Hensrud DD. Vitamin E supplementation in the prevention of coronary heart disease. Mayo Clin Proc. 2001;76(11):1131-6.

4. Liu M, Wallin R, Wallmon A, Saldeen T. Mixed tocopherols have a stronger inhibitory effect on lipid peroxidation than alpha-tocopherol alone. J Cardiovasc Pharmacol. 2002;39(5):714-21.

5. Page JH, Ma J, Chiuve SE, et al. Plasma vitamin B(6) and risk of myocardial infarction in women. Circulation. 2009;120(8):649-55.

6. Van Guelpen B, Hultdin J, Johansson I, et al. Plasma folate and total homocysteine levels are associated with the risk of myocardial infarction, independently of each other and of renal function. J Intern Med. 2009;266(2):182-95.

7. Khandanpour N, Armon MP, Jennings B, et al. Randomized clinical trial of folate supplementation in patients with peripheral arterial disease. Br J Surg. 2009;96(9):990-8.

8. Houston MC, Harper KJ. Potassium, magnesium, and calcium: their role in both the cause and treatment of hypertension. J Clin Hypertens (Greenwich). 2008;10(7 Suppl 2):3-11.

9. Umesawa M, Iso H, Ishihara J, et al. Dietary calcium intake and risks of stroke, its subtypes, and coronary heart disease in Japanese: the JPHC Study Cohort I. Stroke. 2008;39(9):2449-56.

10. Shackebaei D, King N, Shukla B, Suleiman MS. Mechanisms underlying the cardioprotective effect of L-cysteine. Mol Cell Biochem. 2005;277(1-2):27-31.

11. Soukoulis V, Dihu JB, Sole M, et al. Micronutrient deficiencies an unmet need in heart failure. J Am Coll Cardiol. 2009;54(18):1660-73.

12. Singh U, Devaraj S, Jialal I. Coenzyme Q10 supplementation and heart failure. Nutr Rev. 2007;65(6 Pt 1):286-93.

13. Rigault C, Dias JV, Demarquoy J, Le Borgne F. Characteristics of L-carnitine import into heart cells. Biochimie. 2008;90(3):542-6.

14. Singh RB, Aslam M. L-carnitine administration in coronary artery disease and cardiomyopathy. J Assoc Physicians India. 1998;46(9):801-5.

15. Wu YZ, Li SQ, Zu XG, Du J, Wang FF. Ginkgo biloba extract improves coronary artery circulation in patients with coronary artery disease: contribution of plasma nitric oxide and endothelin-1. Phytother Res. 2008;22(6):734-9.

16. Wu Y, Li S, Cui W, Zu X, Du J, Wang F. Ginkgo biloba extract improves coronary blood flow in healthy elderly adults: role of endothelium-dependent vasodilation. Phytomedicine. 2008;15(3):164-9.

17. Jung F, Mrowietz C, Kiesewetter H, Wenzel E. Effect of Ginkgo biloba on fluidity of blood and peripheral microcirculation in volunteers. Arzneimittelforschung. 1990;40(5):589-93.

18. Hsia CH, Shen MC, Lin JS, et al. Nattokinase decreases plasma levels of fibrinogen, factor VII, and factor VIII in human subjects. Nutr Res. 2009;29(3):190-6.

19. Suzuki Y, Kondo K, Ichise H, Tsukamoto Y, Urano T, Umemura K. Dietary supplementation with fermented soybeans suppresses intimal thickening. Nutrition. 2003;19(3):261-4.

20. Bradley JE, Powell AM Jr. Oral calcium EDTA in lead intoxication of children. J Ped. 1954; 45:297-301.

21. Williams JD, Matthews GA, Judd AW. (St. Paul's Hospital) Oral calcium disodium versenate in treatment of lead poisoning. British J Ind Med. 1962;19:211-215.

Additional Health Information

CardioCare™

Supports the Cardiovascular System and Promotes Healthy Circulation*

Product Number: 10820 - 120 Capsules

Dietary Supplement

2 capsules, twice daily.

CardioCare™ provides support for the function of:

    • Heart
    • Arteries
    • Blood Flow
    • Circulation
    • Entire Vascular System


This unique formula will help maintain healthy cholesterol levels and blood pressure balance already within normal range.* For additional cardiovascular and brain support, we recommend Vectomega®, a superior Omega-3 complex.

SUPPLEMENT FACTS

Serving Size: 4 Capsules

Servings Per Container: 30 Amount/Serving Daily Value
Vitamin C (Ascorbic Acid) 400 mg 667 %
Vitamin E (from Mixed Tocopherols) 400 IU 1,334 %
Niacin 20 mg 25 %

Vitamin B6 (as Pyridoxine HCl)

25 mg 1,250 %
Folic Acid 1000 mcg 250 %
Vitamin B12 (as Cyanocobalamin) 1000 mcg 16,667 %
Calcium (from Calcium: Carbonate, Citrate) 200 mg 20 %
Magnesium (Oxide) 200 mg 50 %
Potassium (Chloride) 200 mg 6 %

L-Cysteine (as Cysteine HCl)

200 mg **

CoQ10 (as Ubiquinone)

30 mg **

L-Carnitine HCl

75 mg **

Ginko Biloba Leaf Extract

30 mg **

Nattokinase (1:2100)

75 mg **

EDTA (as Disodium EDTA)

600 mg **

**Daily Value Not Established

Other Ingredients: maltodextrin, magnesium stearate, parsley, vegetable capsule, silica

Contains no: sugar, salt, soy, yeast, wheat, gluten, corn, dairy, artificial coloring, artificial flavoring or preservatives. It contains only natural ingredients. Color variations are normal.

Keep out of reach of children

If pregnant or nursing, consult a health care practitioner before using.

Made in the USA

Europharma
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Did You Know?

The ginkgo tree (Ginkgo biloba) is a living fossil. Ginkgo trees that are 2,000 years or older have been found in Japan and China. One of the reasons for its long survival is its extreme hardiness. Ginkgo is highly resistant to disease, pests, and air pollution. Several ginkgo trees between 1-1.5 miles of the epicenter survived the bombing of Hiroshima (1945) during World War II, even though everything around them was destroyed.

EUROPHARMA USA LIBRARY DISCLAIMER

The research articles and study abstracts that you are about to view in the EuroPharma USA Library were prepared by independent authors and researchers. They are being reproduced on this site in their entirety. No such article or study abstract is intended to promote a particular manufacturer or brand of dietary supplement. This information is not intended to replace the advice of your health care practitioner. If you have any medical conditions, or are taking any prescription or nonprescription medications, see your physician and discuss all aspects of your treatment before altering or discontinuing any course of therapy. Accordingly, individuals must necessarily assume responsibility for their own actions, safety, and health, and the company is not liable or responsible for any loss, injury, or damage allegedly arising from any information posted on this cite.

THIS INFORMATION IS BEING PRESENTED PURSUANT TO SECTION 5 OF THE DIETARY SUPPLEMENT HEALTH AND EDUCATION ACT OF 1994-------THE “E” IN DSHEA—BROUGHT TO YOU AS A PUBLIC SERVICE BY EUROPHARMA USA.