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(How it Works)

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How it Works

Mesoglycan is a naturally-occurring substance found in the body and is critical for building healthy arteries, veins, and blood vessels, and supporting healthy circulation.* It is an excellent source of glycosaminoglycans, the vital and necessary components of the endothelial cells that build the walls of blood vessels and arteries and keep them flexible. Mesoglycan also naturally provides heparan sulfate, another component in the classification of GAGs that also supports blood vessels and healthy circulation.*1

Supplemental mesoglycan has been found to support heart and circulatory concerns throughout the body and balanced fibrinogen levels.* This makes Mesoglycan an excellent choice for supporting not just the cardiovascular system, but veins and blood vessels in the legs, eyes, and brain.* As a porcine source, Mesoglycan is bio-identical and easily utilized by the body.2-5

Heparan sulfate proteoglycans are found in the endothelial cellular walls of arteries and blood vessels. This essential component helps support the structure of veins and helps maintain healthy blood flow through the arteries.*6

Other studies have shown that heparan sulfate is not only critical to the development and maintenance of our arteries, but actually helps balance triglyceride and cholesterol levels as well.*7,8

Because of the properties of this critical ingredient, Mesoglycan is an excellent supplement for maintaining healthy arteries and blood vessels throughout the body, including the heart, eyes, legs, brain, and more.


  1. Tufano A, Arturo C, Cimino E, Di Minno MN, Di Capua M, Cerbone AM, Di Minno G. Mesoglycan: clinical evidences for use in vascular diseases. Int J Vasc Med. 2010;2010:390643. Epub 2010 Aug 31.
  2. Vittoria A, Messa GL, Frigerio C, Celasco G, and Auteri A., “Effect of a single dose of mesoglycan on the human fibrinolytic system, and the profibrinolytic action of nine daily doses,” Int J Tissue React.1988:10(4):61–266.
  3. Caimi G, Romandini S, Lo Presti R, et al. Effect of mesoglycan on macrorheologic and microrheologic parameters. Curr Therapeut Res. 1992;52(3):412–418.
  4. Orefice G, Troisi E, Selvaggio, et al. Effect of long-term mesoglycan treatment on fibrinogen plasma levels in patients with ischemic cerebrovascular disease.  Curr Therapeut Res. 1992;52(5):669-670.
  5. Bettini R, Maino C, Gorini M. Effectiveness of mesoglycan in the prevention of cerebral ischemia. Clin Ter. 2003 Jan-Feb;154(1):13-6.
  6. Adhikari N, Carlson M, Lerman B, Hall JL. Changes in expression of proteoglycan core proteins and heparan sulfate enzymes in the developing and adult murine aorta. J Cardiovasc Transl Res. 2011 Jun;4(3):313-20. doi: 10.1007/s12265-011-9261-7.
  7. Adhikari N, Basi DL, Townsend D, Rusch M, Mariash A, Mullegama S, Watson A, Larson J, Tan S, Lerman B, Esko JD, Selleck SB, Hall JL. Heparan sulfate Ndst1 regulates vascular smooth muscle cell proliferation, vessel size and vascular remodeling. J Mol Cell Cardiol. 2010 Aug;49(2):287-93. doi: 10.1016/j.yjmcc.2010.02.022.
  8. Stanford KI, Wang L, Castagnola J, Song D, Bishop JR, Brown JR, Lawrence R, Bai X, Habuchi H, Tanaka M, Cardoso WV, Kimata K, Esko JD. Heparan sulfate 2-O-sulfotransferase is required for triglyceride-rich lipoprotein clearance. J Biol Chem. 2010 Jan 1;285(1):286-94. doi: 10.1074/jbc.M109.063701.


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Q: What exactly is mesoglycan?

Mesoglycan is a naturally occurring substance found in the body, especially in the heart and blood vessels (veins and arteries). Vascular glycosaminoglycans (or GAGs, sometimes called mucopolysaccharides) are the building blocks of blood vessel walls. Other examples of GAGs include chondroitin and hyaluronic acid. Supplemental mesoglycan has been shown in scientific and clinical studies to support strong, flexible veins and arteries, healthy blood circulation, heart and brain health, and more.*

Q: What is the source for mesoglycan?

Mesoglycan is from a porcine source that provides the form of this nutrient which is best-used by the human body’s cardiovascular system.*

Did You Know?

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There are 60,000 miles of blood vessels in the human body, but it takes only about a minute for a blood cell to make a complete circuit in the body.


Artery Strength and Healthy Circulation*
Heart • Eyes • Legs • Brain

Product Number: 33503 - 30 Capsules

Dietary Supplement

1 capsule daily. For advanced support increase to 2 capsules daily.

Complete Artery and Circulation Support!*

Mesoglycan naturally supports the entire cardiovascular system.*

An excellent source of glycosaminoglycans (GAGs) – necessary building blocks for blood vessels.

Mesoglycan provides an easily utilized source of crucial nutrients for strong veins and arteries. Clinical studies on mesoglycan show amazing benefits:

• Supports blood vessel strength, integrity, and flexibility
• Provides bio-identical mesoglycan compounds shown to
   promote complete circulation support
• Supports healthy blood vessels in the heart, eyes, legs, brain,
   and throughout the body*


Serving Size: 1 Capsule

Servings Per Container: 30 Amount/Serving Daily Value


50 mg **

as a naturally occurring complex of glycosaminoglycans (porcine source)

** Daily Value (DV) not established

Other Ingredients: microcrystalline cellulose, hydroxypropyl methylcellulose, stearic acid, magnesium stearate, silica.

No: sugar, salt, yeast, wheat, gluten, corn, soy, dairy products, artificial coloring, artificial flavoring, or artificial preservatives.


If pregnant or nursing, consult a health care practitioner before using.



The research articles and study abstracts that you are about to view in the EuroPharma USA Library were prepared by independent authors and researchers. They are being reproduced on this site in their entirety. No such article or study abstract is intended to promote a particular manufacturer or brand of dietary supplement. This information is not intended to replace the advice of your health care practitioner. If you have any medical conditions, or are taking any prescription or nonprescription medications, see your physician and discuss all aspects of your treatment before altering or discontinuing any course of therapy. Accordingly, individuals must necessarily assume responsibility for their own actions, safety, and health, and the company is not liable or responsible for any loss, injury, or damage allegedly arising from any information posted on this cite.